Oxidative stress and cell cycle
Our lab is an enthusiastic team of researchers, whose main interest is the characterization of cellular responses to oxidative stress and cell cycle control in the fission yeast, Schizosaccharomyces pombe, using cutting edge approaches in molecular biology, proteomics/mass spectrometry and live cell imaging, as well as traditional genetics.
Recent Publications
- A Transcript-Specific eIF3 Complex Mediates Global Translational Control of Energy Metabolism. Cell Rep. 2016;16(7):1891-902.
- Proteomic Characterization of Reversible Thiol Oxidations in Proteomes and Proteins. Antioxid Redox Signal. 2016
- A functional genome-wide genetic screening identifies new pathways controlling the G1/S transcriptional wave. Cell Cycle 15:720-72.
- Spatiotemporal control of forkheads binding to DNA regulates the meiotic gene expression program. Cell Reports 14:885-895.
- Prp4 kinase grants the license to splice: control of weak splice sites during spliceosome activation. PLoS Genet. 12(1):e1005768.
- Genome-wide Screening of Regulators of Catalase Expression: Role of a Transcription Complex and Histone and tRNA Modification Complexes on Adaptation to Stress. J. Biol. Chem. 291:790-799.
- Distinct biological activity of threonine monophosphorylated MAPK isoforms during the stress response in fission yeast. Cell Signal. 27:2534-2542.
- Promoter nucleosome dynamics regulated by signaling through the CTD code. eLife4:e09008. 2015
- A cascade of iron-containing proteins governs the genetic iron starvation response to promote iron uptake and inhibit iron storage in fission yeast. PLoS Genet. 11(3):e1005106.
- Gel-free proteomic methodologies to study reversible cysteine oxidation and irreversible protein carbonyl formation. Free Radic. Res. 49:494-510.
Address This email address is being protected from spambots. You need JavaScript enabled to view it.Doctor Aiguader, 88. 08003 Barcelona