Experimental Gastroenterology
Our research group is mainly interested in the study of the role of redox signaling in acute inflammation, particularly in acute pancreatitis, and in chronic inflammation, especially in chronic pancreatitis and liver cirrhosis. In addition, our group focuses on the redox regulation of cell cycle, particularly on the role of redox-sensitive p38alpha in the regulation of cytokinesis in the liver.
Recent publications
- Pancreatic Protein Tyrosine Phosphatase 1B Deficiency Exacerbates Acute Pancreatitis in Mice. Am J Pathol. 2016;186(8):2043-54.
- Pancreatic ascites hemoglobin contributes to the systemic response in acute pancreatitis. Free Radic Biol Med. 2015;81:145-55.
- Redox signaling in acute pancreatitis. Redox Biol. 2015;5:1-14.
- Disulfide stress and its targets in acute pancreatitis. Inflamm Allergy Drug Targets. 2014;13(5):312-22.
- Metabolic adaptation and neuroprotection differ in the retina and choroid in a piglet model of acute postnatal hypoxia. Pediatr Res. 2014;76(2):127-34.
- Pancreatic T cell protein-tyrosine phosphatase deficiency ameliorates cerulein-induced acute pancreatitis. Cell Commun Signal. 2014;12:13.
- Disulfide stress: a novel type of oxidative stress in acute pancreatitis. Free Radic Biol Med. 2014;70:265-77.
- Prolonging in utero-like oxygenation after birth diminishes oxidative stress in the lung and brain of mice pups. Redox Biol. 2013;1:297-303.
- Metabolomic Analysis of the Effect of Postnatal Hypoxia on the Retina in a Newly Born Piglet Model. PLoS One. 2013;8(6):e66540.
- Liver-specific p38a deficiency causes reduced cell growth and cytokinesis failure during chronic biliary cirrhosis in mice. Hepatology 2013; 57(5):1950-61.
This email address is being protected from spambots. You need JavaScript enabled to view it.University of Valencia.Department of Physiology, Department of Pharmacy and Pharmaceutical Technology Faculty of Pharmacy, Avda. Vicente Andrés Estellés s/n, 46100 Burjasot (Valencia), Spain